National Health and Medical Research Council

the procedure for reviewing project grants from the National Health and Medical Research Council (NHMRC).

The Australian government's National Health and Medical Research Council (NHMRC), which is comparable to the NIH in the United States, the ANR in France, or the CIHR in Canada, is responsible for allocating funding for biomedical research. The distribution of monies is based on a process of competition. There are a variety of programmes available, including funding for programmes and development. The NHMRC project grant, which is comparable to an NIH R01, is the key programme in the Australian biomedical scene. Half of the NHMRC budget, or more than $400 million AUSD annually, is given to Australian researchers.

The NHMRC project grant peer review process:

Following submission to the NHMRC, a "super panel" (composed of experts in the neurosciences, biochemistry, etc.) is consulted to assess the proposal's conformity. To assign a proposal to the appropriate specialised panel, the key words and proposal summary provided by the applicants are crucial. Members of the panel examine the proposal and disclose any conflicts of interest they may have. Each proposal's scientific merit is assessed by 37 Grant Review Panels, or GRPs (similar to the NIH study section). The GRP members also indicate their prospective subject matter knowledge for a proposal review. The assigner then receives the proposals.

the academy to locate outside reviewers to assess the proposals. Two panel members (the first and second spokespersons) and two outside reviewers each evaluate two ideas. The evaluations are then given to the candidates after the proposal has been rated. Importantly, the grant can only be scored by panellists. The applicants respond to the reviewers, and the first and second spokespersons rate the proposal once again. Whether the suggestion will be discussed at the panel meeting is decided by the panel members.

The scientific quality descriptor:

In order to receive a good rating for the scientific quality, preliminary data are essential. These facts give the reviewers the assurance they need to assess the proposal's viability. Some give a tonne of unfinished information that easily covers a full year or more of research. Large labs, as opposed to smaller labs, have the capacity to generate a significant amount of early data from two or three postdocs. Large labs outperform smaller labs in providing enough data to make the proposal extremely plausible. I also observed that

Senior researchers play it safe and create faultless proposals with every single goal and sub-goal supported by early evidence. However, being continuations of earlier work, these proposals are frequently uninteresting or boring. Junior researchers lack this capacity to generate significant amounts of preliminary data and have less grant writing expertise. They are also employing a riskier strategy. Therefore, it is simple for a reviewer to point out all the errors and lower the proposal's score for its scientific quality.

Significance and Innovation:

It seems obvious to me from all the grants I've read and assessed that junior investigators' applications are more likely to be creative than those of more seasoned researchers. However, because so many facets of these studies are unexplored or unpredictable, these innovative grants are more likely to contain errors. Sadly, evaluators heavily penalise this because they praise project viability more than creative funding methods.

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